Akute Leukämien

• AML Acute myeloid leukemia and related neoplasms
  • AML with recurrent genetic abnormalities
  • AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1
  • AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22);CBFB-MYH11
  • APL with PML-RARA
  • AML with t(9;11)(p21.3;q23.3);MLLT3-KMT2A
  • AML with t(6;9)(p23;q34.1);DEK-NUP214
  • AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2); GATA2, MECOM
  • AML (megakaryoblastic) with t(1;22)(p13.3;q13.3);RBM15-MKL1
  • Provisional entity: AML with BCR-ABL1
  • AML with mutated NPM1
  • AML with biallelic mutations of CEBPA
  • Provisional entity: AML with mutated RUNX1

• AML with myelodysplasia-related changes

• Therapy-related myeloid neoplasms

• AML, NOS
  • AML with minimal differentiation
  • AML without maturation
  • AML with maturation
  • Acute myelomonocytic leukemia
  • Acute monoblastic/monocytic leukemia
  • Pure erythroid leukemia
  • Acute megakaryoblastic leukemia
  • Acute basophilic leukemia
  • Acute panmyelosis with myelofibrosis

• Myeloid sarcoma

• Myeloid proliferations related to Down syndrome
  • Transient abnormal myelopoiesis (TAM)
  • Myeloid leukemia associated with Down syndrome

• Blastic plasmacytoid dendritic cell neoplasm

• Acute leukemias of ambiguous lineage
  • Acute undifferentiated leukemia
  • Mixed phenotype acute leukemia (MPAL) with t(9;22)(q34.1;q11.2); BCR-ABL1
  • MPAL with t(v;11q23.3); KMT2A rearranged
  • MPAL, B/myeloid, NOS
  • MPAL, T/myeloid, NOS

• B-lymphoblastic leukemia/lymphoma
  • B-lymphoblastic leukemia/lymphoma, NOS
  • B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities
  • B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2);BCR-ABL1
  • B-lymphoblastic leukemia/lymphoma with t(v;11q23.3);KMT2A rearranged
  • B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1
  • B-lymphoblastic leukemia/lymphoma with hyperdiploidy
  • B-lymphoblastic leukemia/lymphoma with hypodiploidy
  • B-lymphoblastic leukemia/lymphoma with t(5;14)(q31.1;q32.3) IL3-IGH
  • B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3);TCF3-PBX1
    • Provisional entity: B-lymphoblastic leukemia/lymphoma, BCR-ABL1–like
  • Provisional entity: B-lymphoblastic leukemia/lymphoma with iAMP21

• T-lymphoblastic leukemia/lymphoma
  • Provisional entity: Early T-cell precursor lymphoblastic leukemia
  • Provisional entity: Natural killer (NK) cell lymphoblastic leukemia/lymphoma

Krankheiten